Multisystem inflammatory syndrome in children(MIS-C) is a condition where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. We do not yet know what causes MIS-C. However, we know that many children with MIS-C had the virus that causes COVID-19 or had been around someone with COVID-19. MIS-C can be serious, even deadly, but most children who were diagnosed with this condition have gotten better with medical care.

COVID-19 vaccination is the best protection against MIS-C for children. Researchers found that vaccination reduced the likelihood of MIS-C in children and adolescents by 91%. Children who are not yet old enough to be vaccinated can take everyday actions to avoid virus that causes COVID-19.People 6 months and older should get a COVID-19 vaccination to help protect against COVID-19.

Children diagnosed with MIS-C should discuss COVID-19 vaccination with their clinical care team. The CDC says the benefits of vaccinating children who have had MIS-C outweigh the theoretical risks as long as 90 days have passed since the diagnosis and the child has achieved clinical recovery, including return to baseline heart function. See the CDC’s recommendations for COVID-19 vaccination and MIS-C.