Like all vaccines, COVID-19 vaccines are not 100% effective at preventing infection. Some people who are up to date with their COVID-19 vaccinations will get COVID-19 breakthrough infection. However, staying up to date with your COVID-19 vaccinations means that you are less likely to have a breakthrough infection and, if you do get sick, you are less likely to get severely ill or die. Staying up to date with COVID-19 vaccination also means you are less likely to spread the disease to others and increases your protection against new variants of SARS-CoV-2, the virus that causes COVID-19.