If you received monoclonal antibody therapy or convalescent plasma after exposure or infection, you should delay your COVID-19 vaccination for at least 90 days until more information becomes available, to avoid potential interference of the antibody therapy with vaccine-induced immune responses, according to the Centers for Disease Control and Prevention (CDC).

If you are considering receiving pre-exposure prevention monoclonal antibody therapy (before any exposure to someone with COVID-19), it is recommended that you wait at least two weeks after your last COVID-19 vaccination before receiving this treatment. Pre-exposure prevention treatment is not a substitute for vaccination in individuals for whom COVID-19 vaccination is recommended. You should still receive a COVID-19 vaccination if you are eligible and could benefit from the shot.

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